Small fibroids may not need treatment [1]. The treatment options listed by Cleveland Clinic include medication, myomectomy, uterine artery embolization, and hysterectomy [1]. Medication manages symptoms and, with GnRH agonists and antagonists, can reduce fibroid size while treatment continues. It does not remove fibroids [2]. Myomectomy removes fibroids while preserving uterine tissue [3]. Hysterectomy removes the uterus and means a person cannot become pregnant or have a menstrual period [5]. The table below sets out what the published sources say about each option.
When may no treatment be used?
Cleveland Clinic reports that small fibroids often need no treatment [1].
The symptoms listed by Cleveland Clinic include excessive or painful bleeding during periods, bleeding between periods, a feeling of fullness or bloating in the lower abdomen, frequent urination, pain during sex, low back pain, constipation or rectal pressure, chronic vaginal discharge, inability to empty the bladder completely, and increased abdominal distention [1].
Cleveland Clinic lists heavy menstrual bleeding signs including periods lasting longer than seven days, soaking through a pad or tampon every hour for several hours, needing more than one pad at a time, changing pads during the night, and passing blood clots the size of a quarter or larger several times a day [6].
Heavy bleeding can cause tiredness or shortness of breath from blood loss, which may lead to anemia [6]. Blood work for iron-deficiency anemia includes ferritin and total iron-binding capacity [7].
Which tests are used to assess fibroids?
A uterine fibroid is a growth of muscle and tissue that develops within the wall of the uterus or on its surface [1]. Cleveland Clinic lists intramural, submucosal, subserosal, and pedunculated fibroids [1].
Tests used to find or assess fibroids include ultrasonography, magnetic resonance imaging, computed tomography, hysteroscopy, hysterosalpingography, sonohysterography, and laparoscopy [1]. Tests listed for heavy bleeding include pelvic ultrasound, blood tests, transvaginal ultrasound, MRI, Pap test, cervical culture, endometrial biopsy, sonohysterogram, and hysteroscopy [6].
Ask:
“What does my imaging show, and which treatment options fit that finding?”
What can medication do?
Medication for fibroids manages symptoms. GnRH agonists and antagonists reduce fibroid size while treatment continues, but medication does not remove fibroids [2]. The review says there is no available treatment option that permanently stops fibroid tumor growth, and fibroid symptoms return after effective therapies stop [2].
Cleveland Clinic lists over-the-counter pain medication, iron supplements, birth control options, GnRH agonists, elagolix, and tranexamic acid among medication options for fibroids [1].
Tranexamic acid significantly reduced fibroid-associated heavy menstrual bleeding in reviewed evidence, but it did not treat the fibroid directly, and there are no long-term treatment data [2]. The review reports limited direct data for contraceptive hormones in fibroid-associated heavy menstrual bleeding and a lack of evidence for progestogens in that setting [2].
Several studies reported decreased menstrual bleeding, pelvic pain, and leiomyoma size in women treated with elagolix or relugolix [2]. Cleveland Clinic lists GnRH agonists as medicines that shrink fibroids temporarily [1].
Iron-deficiency anemia treatment includes oral iron supplements taken by mouth or iron given intravenously as an infusion [7].
Which procedure removes fibroids while preserving uterine tissue?
A myomectomy removes uterine fibroids while preserving the tissues of the uterus so that pregnancy remains possible [3]. The approaches listed by Cleveland Clinic are hysteroscopic, laparoscopic or robotic, and open abdominal myomectomy [3].
Fibroids can appear again after a myomectomy [3]. Cleveland Clinic reports that the risk of developing more later is higher for patients below age 40 who already have several fibroids [3]. Listed risks include bleeding, infection, blood clots, damage to nearby organs, reaction to anesthesia, and an increased chance of needing a cesarean delivery [3].
What is uterine artery embolization?
Cleveland Clinic describes uterine artery embolization as a minimally invasive treatment used most often for fibroid-related vaginal bleeding [4]. Because it works through a tiny puncture, it is less invasive than myomectomy or hysterectomy [4].
Menstrual cycles shut down permanently in about 1% to 5% of people after the procedure [4]. Uterine artery embolization should not be performed in someone with a pelvic infection or an allergic reaction to contrast dyes [4].
What does hysterectomy change?
A hysterectomy is the surgical removal of the uterus and, most likely, the cervix [5]. After surgery, a person cannot become pregnant and will not get a menstrual period [5].
The ovaries are not always removed during a hysterectomy. Whether they are removed depends on the type of surgery and the reason for it [5].
A total hysterectomy removes the uterus and cervix. A supracervical hysterectomy removes the upper part of the uterus and leaves the cervix. A total hysterectomy with bilateral salpingo-oophorectomy also removes the fallopian tubes and ovaries, which triggers immediate menopause. A radical hysterectomy also removes the upper vagina and surrounding tissue and is typically used for cancer [5].
Hysterectomy is listed as a treatment for heavy menstrual bleeding [6].
How often were these procedures used in US inpatient encounters?
Across 271,885 US inpatient fibroid encounters from 2016 to 2022, hysterectomy accounted for 73.4% of procedures, myomectomy 23.1%, and uterine fibroid embolization 3.5% [8].
In the same analysis, Black patients had higher odds of undergoing uterine fibroid embolization than hysterectomy compared with white patients. The adjusted odds ratio was 1.64, with a 95% confidence interval of 1.44 to 1.87 [8].
How do the options compare?
| Option | What it does to bleeding | What it does to the fibroid | Uterus kept or not | Recovery window | What the recurrence data say |
|---|---|---|---|---|---|
| No treatment | No treatment effect is listed | Small fibroids often need no treatment [1] | Not stated | No procedure recovery window listed | No recurrence data listed |
| Medication | Can reduce heavy bleeding; evidence is limited for some options [2] | Does not remove fibroids; some GnRH agonists and antagonists reduce size while treatment continues [1][2] | Not stated | No procedure recovery window listed | Symptoms return after effective therapy stops [2] |
| Myomectomy | Appears in the treatment list for heavy menstrual bleeding [6] | Removes fibroids [3] | Preserved [3] | Days after hysteroscopic surgery, two to four weeks after laparoscopic surgery, and up to six weeks at home after open surgery [3] | Fibroids can appear again [3] |
| Uterine artery embolization | Used most often for fibroid-related vaginal bleeding [4] | No action on the fibroid is stated in the source | Not stated | Most people resume activity in the first one to two weeks [4] | 32% had symptoms five years later [4] |
| Hysterectomy | Ends menstrual periods [5] | Removes the uterus [5] | Not kept [5] | Generally four to six weeks [5] | No recurrence outcome is listed [5] |
Radiofrequency ablation and endometrial ablation appear in published treatment lists for fibroids and heavy bleeding alongside myomectomy, embolization, and hysterectomy [1].
What should you ask before choosing?
- What does my imaging show?
- Which options are listed for my bleeding?
- Does this treatment manage symptoms, reduce fibroid size while treatment continues, or remove fibroids?
- Does this procedure preserve uterine tissue?
- What recovery window applies to the specific approach?
- What later-symptom or recurrence data are available?
- If medication is offered, what happens after effective treatment stops?
- If hysterectomy is offered, will my ovaries be removed?
- Should blood work include ferritin and total iron-binding capacity [7]?
What to do next
- Write down the number of pads or tampons used during the heaviest hour, whether bleeding lasts longer than seven days, and whether you pass quarter-sized clots [6].
- Record bleeding between periods, bleeding after sex, pain, pressure, urinary symptoms, constipation, tiredness, or shortness of breath [1][6].
- Bring your imaging report and ask, “What does my imaging show, and which treatment options fit that finding?”
- Ask whether you need pelvic or transvaginal ultrasound, MRI, blood tests, or another listed test [1][6].
- Ask whether blood work should include ferritin and total iron-binding capacity [7].
- Say, “Please compare the options by bleeding control, uterine tissue, recovery, and what happens after treatment stops.”
- If you are soaking at least two pads or tampons per hour across two to three consecutive hours, seek prompt professional evaluation [6].
- If medication is offered, ask, “Does this remove the fibroid, or does it manage symptoms while I take it?” [2]
- If a procedure is offered, ask for its recovery window and the later-symptom or recurrence data available for that option.
- If hysterectomy is offered, ask, “Will my ovaries be removed, and which type of hysterectomy is being offered?” [5]
Related on Ruby: medications for fibroids and alternatives to hysterectomy
Sources
- Cleveland Clinic, Uterine fibroids. https://my.clevelandclinic.org/health/diseases/9130-uterine-fibroids
- Barseghyan 2023, The efficacy of medical management of leiomyoma-associated heavy menstrual bleeding, F&S Reports, PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC10958631/
- Cleveland Clinic, Myomectomy. https://my.clevelandclinic.org/health/treatments/15448-myomectomy
- Cleveland Clinic, Uterine artery embolization. https://my.clevelandclinic.org/health/treatments/17954-uterine-artery-embolization
- Cleveland Clinic, Hysterectomy. https://my.clevelandclinic.org/health/treatments/4852-hysterectomy
- Cleveland Clinic, Menorrhagia (heavy menstrual bleeding). https://my.clevelandclinic.org/health/diseases/17734-menorrhagia-heavy-menstrual-bleeding
- Cleveland Clinic, Iron-deficiency anemia. https://my.clevelandclinic.org/health/diseases/22824-iron-deficiency-anemia
- Elhakim 2025, Disparities in utilization of uterine fibroid embolization, JAMA Network Open, PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC12441870/